Delay correction for the assessment of blood-brain barrier permeability using first-pass dynamic perfusion CT.

نویسندگان

  • T Schneider
  • J Hom
  • J Bredno
  • J W Dankbaar
  • S-C Cheng
  • M Wintermark
چکیده

SUMMARY Hemorrhagic transformation is a serious potential complication of ischemic stroke with damage to the BBB as one of the contributing mechanisms. BBB permeability measurements extracted from PCT by using the Patlak model can provide a valuable assessment of the extent of BBB damage. Unfortunately, Patlak assumptions require extended PCT acquisition, increasing the risk of motion artifacts. A necessary correction is presented for obtaining accurate BBB permeability measurements from first-pass PCT.

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عنوان ژورنال:
  • AJNR. American journal of neuroradiology

دوره 32 7  شماره 

صفحات  -

تاریخ انتشار 2011